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</html>";s:4:"text";s:15154:"To explore the role of endophytic bacteria from a medicinal plant in the production of bioactive compounds, bacterial strains (10 different taxa) were isolated from the surface sterilized stem of healthy Ephedra foliata. To replace the conventional extraction techniques, new techniques as highpressure extraction processes that use environment friendly solvents have been developed. Supercritical Fluid Extraction of Bioactive Compounds from Fruits and Vegetables. Ultrasound-assisted extraction (UAE) has been used in diverse applications of food-processing technology to extract bioactive compounds from plant materials [ 19 ]. the important bioactive compounds (List of Medicinal plants Table 3). Several studies suggest that endophytic bacteria isolated from medicinal plants can produce the same or similar bioactive compounds as their host plant including novel compounds (Mehanni and Safwat, 2009; Alvin et al., 2014; Gouda et al., 2016). Bioactive compounds are largely obtained from medicinal plants. Firstly, extraction of bioactive compounds from plants Secondly, selectivity if the analytical methods needs to be increased Thirdly, sensitivity of the bioassay is increased by increasing the concenteration of targeted compounds Fourthly, detection and Separation of bioactive compounds into a suitable compound Extraction of bioactive compounds by conventional extraction methods. The aim of the present study was to screen the content of total polyphenols, flavonoids, and condensed tannins together with the radical scavenging capacity and the antimicrobial activity of leaves, fruits and seeds extracts  Therefore there is need to search for plants with medicinally valuable and excellent extracts produced from widely varying substrates. Extraction of bioactive compounds from medicinal plants has been permitted the demonstration of their physiological activity by medicinal researcher. They have displayed pronounced efficacy as anticancer, antitumour and antimicrobial agents in various pharmacological studies. Figure 1 Arbutus pavarii Pamp is a medicinal plant commonly used by local tribes in East Libya for the treatment of many diseases, such as gastritis, renal infections, cancer and kidney diseases. The sample preparation such as grinding and drying affected the efficiency and phyto chemical constituents of the final Separation Techniques used in Purification and  Characterisation of Bioactive Compounds: The  crude extract of medicinal plant usually has various  types  of  metabolites  bearing  different  polarities. Therefore  it  is  a  big  challenge  to  separate  the  particular  compound  on  the  basis  of  its  identification  and  characterization. Thus, the extraction of active compounds from plants needs appropriate extraction methods and techniques that provide bioactive ingredients rich extracts and fractions. Raghuraj Singh, Raghuraj Singh. plant chemical compounds or bioactive componen ts are often referred to as phytochemicals ( phyto- from Greek - phyto meaning plant ) or phytoconstituents and are responsible for protecting the plant against microbial infections or infestations by pests (Abo et al., 1991; Liu, 2004; Nweze et al., 2004; Doughari et al., 2009). Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Background Neorautanenia mitis, Hydnora abyssinica, and Senna surattensis are medicinal plants with a variety of traditional uses. Objectives of Plant Extraction: 1.Firstly, extraction of bioactive compounds from plants 2.Secondly, selectivity if the analytical methods  A sum of 20,000 plants has been identified in 91 countries that contain medicinal properties. Bioactive compounds and extracts from Piper species have been examined and found to be of clinical importance for both malignant and non-malignant diseases. Science Food &  Tamarindus indica is one of the tropical medicinal plants that has been attributed curative potential of numerous diseases by many rural dwellers. Bitter Melons Bioactive Compounds. Abstract. This new volume explores the importance of phytochemicals from plants in therapeutics, focusing on the extraction of bioactive compounds and their applications in human health. INTRODUCTION  Although, the various classes of preparations involving simple expression, aqueous hot and cold extraction and evaporation were in vogue since long time but, real and scientific rapid progress in the extraction procedures for medicinal plant's preparations was made after 19th century. Extraction, isolation and characterization of bioactive compounds from plants' extracts Abstract Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Typically, it is extracted from plant matrices using conventional methods such as maceration, sonication, infusion, and Soxhlet extraction with high solvent consumption. Here, we have elucidated the anti-tumor effects of Cinnamomum zeylanicum extract (CZE) and its bioactive compound cinnamaldehyde (CIN) on oral cancer and elucidated underlying molecular mechanisms. Biocompound Extraction Preparation All stages of extractions, from the pre-extraction and extraction are equally important in the study of medicinal plants. Natural products and their bioactive compounds are increasingly utilized in preventive and therapeutic medication as well as for the production of pharmaceutical supplements and, more recently, as food   Vardanega R., Santos D.T., Meireles M.A.M. Multiple solvents have been commonly used to extract phytochemicals, and scientists usually employed a dried powder of plants to extract bioactive compounds and eliminate the interference of water at the same time. Solvents used for the extraction of biomolecules from plants are chosen based on the polarity of the solute of interest. Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. 2020a, b). J. Food Sci. Infusion is a simple chemical process used for extraction of plant materials that are volatile and dissolve readily or release their active ingredients easily in organic solvents. Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Methods Used for Bioactive Compound Extraction, Isolation, and Purication 2.1. The chapter provides an overview of recent studies which have identified optimal conditions for isolating particular bioactives using these techniques. Ultrasound, with levels greater than 20 kHz, is used to disrupt plant cell walls, which helps improve the solvents ability to penetrate the cells and obtain a higher extraction yield. process of isolation of pure bioactive components  from  medicinal  plants  is  a  long  and  tiresome  process. The new useful compounds derived from  plants and their screening for chemical structure are  performed  for  isolation  of  new  targets  with  Medicinal plants are a source of great economic value all over the world. In this project, we have done comparative studies of the metabolite extracted from five different medicinal plants on human pathogen i.e E. coli and P. aeruginosa. The most important bioactive (chemical) compounds of plants are alkaloids, flavonoids, tannins and phenol compounds. This review is aimed to discuss different extraction techniques along with their basic mechanism for extracting bioactive compounds from medicinal plants. Several studies suggest that endophytic bacteria isolated from medicinal plants can produce the same or similar bioactive compounds as their host plant including novel compounds (Mehanni and Safwat, 2009; Alvin et al., 2014; Gouda et al., 2016). It presents new research on bioactive compounds in medicinal plants that provide health benefits, including those that have proven especially effective in treating and managing diabetes mellitus and hypertension. Medicinal plants have been used as holistic therapies to support human health and wellbeing all over the world. Characterisation of Bioactive Compounds: The crude extract of medicinal plant usually has various types of metabolites bearing different polarities. Therefore it is a big challenge to separate the particular compound on the basis of its identification and characterization. Extraction techniques of actives compounds from plants and herbs Extraction is separating the medicinally active mixture of many naturally active compounds usually contained inside plant materials (tissues) using selective solvents through the standard procedure [ 50 ]. Soxhlet extraction of bioactive compounds is a long established practice, which is useful to apply when the bioactive compounds from a material have limited solubility into a particular solvent. The microwave- assisted extraction (MAE) system is an efficient technique under the optimal condition in the extraction of bioactive chemical compounds E- and Z- guggolsterone, cinnamaldehyde and tannin from the plants has been investigated. Full Article. In this study, we sought to isolate the bioactive compounds responsible for some of these activities, and to uncover their other potential medicinal properties. Murraya Koenigii (Meethi Neem), Curcuma longa (Turmeric), Achyranthes aspera (Latjira), Withania Somnifera (Ashwagandha) and Syzygium cumini (Jamun) are being widely used in ayurvedic/traditional  Plants generally contain only a small amount of active compounds, but in most cases its high value justifies the development of the high-performance process. and Z. mauritiana Lam., as a widespread species in Tunisia, are well known for their medicinal and food uses. Extraction is the first and most important step in the analysis of medicinal plants because it is necessary to extract the desired chemical components from plant materials for further separation and characterization.  The reader is invited to learn about the huge potential of these techniques for extraction of high added-value compounds (with improved bioactivity) while complying with Green Chemistry goals. EXTRACTION, ISOLATION AND CHARACTERIZATION OF BIOACTIVE COMPOUNDS FROM PLANTS' EXTRACTS Type: Article Abstract: Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. More than 8000 different phenolic compounds have been characterized; fruits and vegetables are the prime sources of natural antioxidants. Researchers have shown interest in extracting bioactive compounds because of their human health benefits and characteristics  Methods The DCM and ethanol extracts of the roots of N. mitis and H.  Biography : Balunkeswar Nayak is an Assistant Professor of Food Processing at the School of Food & Agriculture in the University of  Bioactive compounds of plant origin have been defined as natural chemical compounds present in small amounts in plants. 04. Soxhlet extraction of bioactive compounds is a long established practice, which is useful to apply when the bioactive compounds from a material have limited solubility into a particular solvent. 2. Use of non-conventional extraction techniques as green techniques for bioactive compounds extraction. The medicinal value of plant lies in its bioactive phytochemical constituents that produce definite physiological actions on the human body and these phytochemicals are produced as secondary metabolites to defend the plant from the environment. This review is aimed to discuss different extraction techniques along with their basic mechanism for extracting bioactive compounds from medicinal plants. The plants are the reservoirs of naturally occurring chemical compounds and of structurally diverse bioactive molecules. Characterisation of Bioactive Compounds: The crude extract of medicinal plant usually has various types of metabolites bearing different polarities. Soxhlet extraction of bioactive compounds is a long established practice, which is useful to apply when the bioactive compounds from a material have limited solubility into a particular solvent. (Lam.) The optimized conditions for the extraction of bioactive components from medicinal plants were determined using two-factor central composite design (CCD) combined with response surface methodology (RSM). The Cannabis industry is rapidly growing; therefore, product development and extraction methods have become crucial aspects of Cannabis research. Highlights Bioactive compounds of plant materials. The processed intended to soften and break the plants cell wall to release the soluble phytochemicals. The increasing identification of biologically active species and isolation of bioactive compounds is correlated to an increasing number of microalgae species being successfully grown in culture (Kiuru et al., 2014).There are only a few studies where a large number of microalgae species were screened for antimicrobial activity e.g. Ziziphus lotus L. The flavonoids are compounds synthesized by plants, and they have properties such as antioxidant, anticancer, anti-inflammatory, and antibacterial, among others. In this review, recent advances in greener technology for extracting natural bioactive components from plant origin sources are discussed. Synthetic antioxidants have side toxic effects whilst natural antioxidants, such as flavonoids from natural sources, have relatively low toxicity. The results show that, this method provides a fast and easy procedure for the extraction compared to the conventional extraction  The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working  Aromatic Plants (2015), pp. Process Design for the Extraction of Bioactive Compounds from Several Mediterranean Medicinal Plants Konstantina M. Laina*, Panagiota N. Eleni, Konstantina G. Tsitseli, Magdalini K.  Greece has a long history of medicinal plants and herbs, with extensive literature and clinical applications covering thousands of years (Solomou et al., 2015). One of the most important bioactive properties of flavonoids is their antioxidant effect. This volume sheds new light on the immense potential of medicinal plants for human health from different technological aspects. Essential oils are compounds extracted from plants. 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